CBD can be effective during the early stages of psychosis, as it has antipsychotic effects. The compound affects brain chemistry with minimal side effects, such as diarrhea. In addition, there is some evidence that CBD does not interact with antipsychotic medications. Although more studies are needed on CBD and schizophrenia, a good deal of research suggests that CBD could be useful for people with schizophrenia.
In particular, it could be a potential treatment for psychosis. Because CBD products are not regulated by the Food and Drug Administration (FDA), some companies mislabel CBD products. Next, we synthesize the current evidence on the clinical efficacy of CBD in terms of positive, negative and cognitive symptoms, its safety and tolerability, and the possible mechanisms by which CBD may have antipsychotic effects. This is the first time that research has scanned the brains of people with a diagnosis of psychosis who have taken CBD and, although the sample is small, the results are convincing, as they show that CBD influences the same areas of the brain that have been shown to have unusual activity in people with psychosis, said the study's lead author, Sagnik Bhattacharyya, MD, PhD.
This includes preclinical work, experimental studies in healthy human volunteers comparing the neurocognitive effects of THC and CBD, as well as studies that examine whether CBD can block or mitigate the symptomatic effects of THC. This is an excerpt from The Essential Guide to CBD from the publishers of Reader's Digest and Project CBD. While CBD is currently being tested in relation to a range of psychiatric disorders and physical health conditions,12 this review synthesizes and summarizes the current evidence on the therapeutic potential of CBD as a treatment for psychosis. However, in Boggs's study, 55% of the CBD group and 72% of the placebo group were taking second-generation antipsychotics, while 50% of the CBD group and 28% of the placebo group were taking first-generation antipsychotics.
